What Is GHRP-2?

GHRP-2 (pralmorelin) is a second-generation growth-hormone-releasing peptide — for years the standard secretagogue before ipamorelin displaced it. It triggers strong GH pulses via the ghrelin receptor with moderate appetite stimulation and mild cortisol/prolactin activity.

It holds one distinction: in Japan it achieved actual pharmaceutical approval as a diagnostic agent for GH deficiency testing — rare legitimacy for this family.

What is GHRP-2 studied for?

Side effects & safety

Moderate appetite increase, water retention, mild cortisol/prolactin elevation at higher doses, occasional tingling/flushing. A known, manageable profile — just a less clean one than ipamorelin's.

Legal & approval status

Approved only as a diagnostic in Japan; elsewhere research chemical. WADA-banned.

Typical dosing at a glance

Commonly reported protocols use 100 mcg–300 mcg, 1–3x daily, via subcutaneous injection. For the mixing math — how much bacteriostatic water, exact syringe units, doses per vial — see the GHRP-2 reconstitution calculator →

Related peptides

What is Ipamorelin?What is CJC-1295 (no DAC)?What is CJC-1295 DAC?What is Sermorelin?What is Tesamorelin?

Educational overview based on published research and commonly reported community protocols — not medical advice, and not an endorsement of any compound. Consult a licensed healthcare provider.