LL-37 Reconstitution & Dosing
Also known as: Cathelicidin
Quick answer: mix a 5 mg vial of LL-37 with 2.5 ml of bacteriostatic water. That gives 2.00 mg/ml, so a typical 100 mcg dose is 5.0 units on a U-100 insulin syringe — about 50 doses per vial. Reported protocols range 50 mcg–100 mcg, daily.
LL-37 is the only human cathelicidin antimicrobial peptide, studied for biofilm disruption and immune modulation. Reported research doses are small — most protocols stay at or under 100 mcg daily. Full overview: what is LL-37? →
Calculate your exact dose
Typical range: 50 mcg–100 mcg, daily
LL-37 mixing chart — 5 mg vial
Units to draw for a 100 mcg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 100 mcg dose = | Per unit |
|---|---|---|---|
| 1 ml | 5.00 mg/ml | 2.0 units | 50.0 mcg |
| 2 ml | 2.50 mg/ml | 4.0 units | 25.0 mcg |
| 2.5 ml ← typical | 2.00 mg/ml | 5.0 units | 20.0 mcg |
| 3 ml | 1.67 mg/ml | 6.0 units | 16.7 mcg |
| 5 ml | 1.00 mg/ml | 10 units | 10.0 mcg |
Protocol reference
FAQ
How much bacteriostatic water do you add to LL-37?+
Most protocols mix a 5 mg vial of LL-37 with 2.5 ml of bacteriostatic water. This gives 2.00 mg/ml, so a typical 100 mcg dose is 5.0 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical LL-37 dose?+
Commonly reported LL-37 protocols use 50 mcg to 100 mcg, daily, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 5 mg vial of LL-37?+
At 100 mcg per dose, a 5 mg vial contains about 50 doses, regardless of how much water you add.
How should LL-37 be stored?+
Reconstituted: refrigerate, typically used within 4 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. LL-37 may not be approved for human use in your jurisdiction.