PT-141 Reconstitution & Dosing
Also known as: Bremelanotide, Vyleesi
Quick answer: mix a 10 mg vial of PT-141 with 2 ml of bacteriostatic water. That gives 5.00 mg/ml, so a typical 1 mg dose is 20 units on a U-100 insulin syringe — about 10 doses per vial. Reported protocols range 500 mcg–2 mg, as needed, 45min–2h before activity.
PT-141 (bremelanotide) is a melanocortin agonist FDA-approved as Vyleesi for low sexual desire in women, and widely used off-label by men. It works through the nervous system, not blood flow — a different mechanism than Viagra-class drugs. Full overview: what is PT-141? →
Calculate your exact dose
Typical range: 500 mcg–2 mg, as needed, 45min–2h before activity
PT-141 mixing chart — 10 mg vial
Units to draw for a 1 mg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 1 mg dose = | Per unit |
|---|---|---|---|
| 1 ml | 10.00 mg/ml | 10 units | 100.0 mcg |
| 2 ml ← typical | 5.00 mg/ml | 20 units | 50.0 mcg |
| 2.5 ml | 4.00 mg/ml | 25 units | 40.0 mcg |
| 3 ml | 3.33 mg/ml | 30 units | 33.3 mcg |
| 5 ml | 2.00 mg/ml | 50 units | 20.0 mcg |
Protocol reference
FAQ
How much bacteriostatic water do you add to PT-141?+
Most protocols mix a 10 mg vial of PT-141 with 2 ml of bacteriostatic water. This gives 5.00 mg/ml, so a typical 1 mg dose is 20 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical PT-141 dose?+
Commonly reported PT-141 protocols use 500 mcg to 2 mg, as needed, 45min–2h before activity, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 10 mg vial of PT-141?+
At 1 mg per dose, a 10 mg vial contains about 10 doses, regardless of how much water you add.
How should PT-141 be stored?+
Reconstituted: refrigerate, typically used within 4–6 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. PT-141 may not be approved for human use in your jurisdiction.