Melanotan II Reconstitution & Dosing

Also known as: MT2, MT-2

Quick answer: mix a 10 mg vial of Melanotan II with 2 ml of bacteriostatic water. That gives 5.00 mg/ml, so a typical 250 mcg dose is 5.0 units on a U-100 insulin syringe — about 40 doses per vial. Reported protocols range 100 mcg500 mcg, daily during loading, then 1–2x weekly.

Melanotan II is a melanocortin agonist that stimulates melanin production for tanning with minimal UV exposure. Protocols start very low (100 mcg) to gauge nausea and flushing response before scaling. Full overview: what is Melanotan II? →

Start-low matters: side effects (nausea, flushing) are dose-dependent and front-loaded.

Calculate your exact dose

Typical range: 100 mcg500 mcg, daily during loading, then 1–2x weekly

5.0 units
to draw on a U-100 insulin syringe (0.05 ml)
Concentration: 5.00 mg/ml (50.0 mcg per unit)
Doses per vial: 40
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Syringe fill (100-unit / 1 ml insulin syringe)

Melanotan II mixing chart — 10 mg vial

Units to draw for a 250 mcg dose at different water amounts. More water never changes the dose — only the volume you measure.

Water addedConcentration250 mcg dose =Per unit
1 ml 10.00 mg/ml2.5 units100.0 mcg
2 ml ← typical5.00 mg/ml5.0 units50.0 mcg
2.5 ml 4.00 mg/ml6.3 units40.0 mcg
3 ml 3.33 mg/ml7.5 units33.3 mcg
5 ml 2.00 mg/ml13 units20.0 mcg

Protocol reference

Common vial sizes
10 mg
Reported dose range
100 mcg – 500 mcg
Frequency
daily during loading, then 1–2x weekly
Administration
subcutaneous injection
Storage
Reconstituted: refrigerate, typically used within 4–6 weeks.

FAQ

How much bacteriostatic water do you add to Melanotan II?+

Most protocols mix a 10 mg vial of Melanotan II with 2 ml of bacteriostatic water. This gives 5.00 mg/ml, so a typical 250 mcg dose is 5.0 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.

What is a typical Melanotan II dose?+

Commonly reported Melanotan II protocols use 100 mcg to 500 mcg, daily during loading, then 1–2x weekly, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.

How many doses are in a 10 mg vial of Melanotan II?+

At 250 mcg per dose, a 10 mg vial contains about 40 doses, regardless of how much water you add.

How should Melanotan II be stored?+

Reconstituted: refrigerate, typically used within 4–6 weeks.

Related peptides

Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. Melanotan II may not be approved for human use in your jurisdiction.