BPC-157 + KPV (Gut Stack)
The go-to combination in gut-health protocols (IBD, leaky-gut and post-antibiotic contexts in the research literature). BPC-157 — itself derived from a gastric protein — supports mucosal repair and angiogenesis, while KPV, the anti-inflammatory fragment of alpha-MSH, quiets the inflammatory signaling that keeps gut lining irritated. Repair plus calm-down, in parallel.
Components & typical mixing
| Peptide | Typical dose | Typical mix | Units/dose |
|---|---|---|---|
| BPC-157 | 250 mcg–500 mcg, 1–2x daily | 5 mg + 2 ml | 10 units = 250 mcg |
| KPV | 200 mcg–500 mcg, daily | 5 mg + 2 ml | 10 units = 250 mcg |
How the protocol is typically run
- →BPC-157: 250–500 mcg daily. For gut targets, oral/intragastric dosing is uniquely defensible for this peptide — it's stable in gastric juice, which is exactly where it was discovered.
- →KPV: 200–500 mcg daily, subcutaneous or oral in gut protocols.
- →Typical run: 4–8 weeks alongside dietary work — the stack supports a healing environment; it doesn't out-repair a diet that keeps re-injuring the gut.
Cautions
Gut symptoms have real differential diagnoses (celiac, IBD, infection) that deserve actual workup. Self-treating persistent GI issues with research peptides instead of a colonoscopy is how serious conditions get found late.
Other stacks
Educational reference describing commonly published protocols — not medical advice. Most compounds referenced are research chemicals without approval for human use.