What Is Hexarelin?

Hexarelin is a hexapeptide secretagogue — the most potent GH-releaser per microgram of the GHRP family, developed in the 1990s. It hits the same ghrelin receptor as ipamorelin but harder, at the cost of selectivity and staying power.

Its scientific footnote is cardiac: animal studies show cardioprotective effects (via CD36 receptor binding) partly independent of GH release, keeping research interest alive even as protocols moved to cleaner molecules. Its receptor desensitizes quickly, so use is short-cycle by necessity.

What is Hexarelin studied for?

Side effects & safety

The GHRP set: cortisol and prolactin elevation (strongest of the family), water retention, flushing. Rapid receptor desensitization is the practical limiter — more is quickly less.

Legal & approval status

Research chemical; no approvals. WADA-banned.

Typical dosing at a glance

Commonly reported protocols use 100 mcg–200 mcg, 1–3x daily, via subcutaneous injection. For the mixing math — how much bacteriostatic water, exact syringe units, doses per vial — see the Hexarelin reconstitution calculator →

Related peptides

What is Ipamorelin?What is CJC-1295 (no DAC)?What is CJC-1295 DAC?What is Sermorelin?What is Tesamorelin?

Educational overview based on published research and commonly reported community protocols — not medical advice, and not an endorsement of any compound. Consult a licensed healthcare provider.