Tirzepatide Reconstitution & Dosing
Also known as: Mounjaro, Zepbound, GIP/GLP-1
Quick answer: mix a 10 mg vial of Tirzepatide with 2 ml of bacteriostatic water. That gives 5.00 mg/ml, so a typical 2.5 mg dose is 50 units on a U-100 insulin syringe — about 4 doses per vial. Reported protocols range 2.5 mg–15 mg, 1x weekly, titrated up.
Tirzepatide is a dual GIP/GLP-1 agonist (Mounjaro, Zepbound) with the strongest weight-loss data of any approved incretin. Vials run larger than semaglutide (up to 30 mg), so double-checking concentration before drawing is critical. Full overview: what is Tirzepatide? →
Calculate your exact dose
Typical range: 2.5 mg–15 mg, 1x weekly, titrated up
Tirzepatide mixing chart — 10 mg vial
Units to draw for a 2.5 mg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 2.5 mg dose = | Per unit |
|---|---|---|---|
| 1 ml | 10.00 mg/ml | 25 units | 100.0 mcg |
| 2 ml ← typical | 5.00 mg/ml | 50 units | 50.0 mcg |
| 2.5 ml | 4.00 mg/ml | 63 units | 40.0 mcg |
| 3 ml | 3.33 mg/ml | 75 units | 33.3 mcg |
| 5 ml | 2.00 mg/ml | 125 units (>1 syringe) | 20.0 mcg |
Protocol reference
FAQ
How much bacteriostatic water do you add to Tirzepatide?+
Most protocols mix a 10 mg vial of Tirzepatide with 2 ml of bacteriostatic water. This gives 5.00 mg/ml, so a typical 2.5 mg dose is 50 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical Tirzepatide dose?+
Commonly reported Tirzepatide protocols use 2.5 mg to 15 mg, 1x weekly, titrated up, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 10 mg vial of Tirzepatide?+
At 2.5 mg per dose, a 10 mg vial contains about 4 doses, regardless of how much water you add.
How should Tirzepatide be stored?+
Reconstituted: refrigerate; typically used within 4–8 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. Tirzepatide may not be approved for human use in your jurisdiction.