What Is HGH Fragment 176-191?

Also known as: Frag 176-191

HGH Fragment 176-191 is the raw lipolytic tail of the growth hormone molecule — the same region AOD-9604 stabilizes. It represents the original insight: GH's fat-burning signal lives in its final 16 amino acids and can be separated from the rest of the hormone's effects.

Research is mostly preclinical: rodent studies show increased fat breakdown and reduced fat storage without changes in blood glucose or IGF-1. It is functionally interchangeable with AOD-9604 in community protocols, chosen mainly on price.

What is HGH Fragment 176-191 studied for?

Side effects & safety

Mild by report — injection-site reactions primarily. It is a fragile molecule; degraded product (from heat or shaking) is the more common practical problem than side effects.

Legal & approval status

Research chemical, no approvals, WADA-banned. The unstabilized sibling of AOD-9604.

Typical dosing at a glance

Commonly reported protocols use 250 mcg–500 mcg, 1–2x daily, fasted, via subcutaneous injection. For the mixing math — how much bacteriostatic water, exact syringe units, doses per vial — see the HGH Fragment 176-191 reconstitution calculator →

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Educational overview based on published research and commonly reported community protocols — not medical advice, and not an endorsement of any compound. Consult a licensed healthcare provider.