Survodutide Reconstitution Calculator & Dosage Chart
Also known as: BI 456906, GLP-1/glucagon dual agonist
Quick answer: mix a 10 mg vial of Survodutide with 2 ml of bacteriostatic water. That gives 5.00 mg/ml, so a typical 2.4 mg dose is 48 units on a U-100 insulin syringe — about 4 doses per vial. Reported protocols range 600 mcg–6 mg, 1x weekly, titrated up over ~20 weeks.
Survodutide is Boehringer Ingelheim's investigational GLP-1/glucagon dual agonist, in phase 3 trials for obesity and MASH. Phase 2 data showed up to ~19% weight loss at 4.6 mg after 46 weeks. Not approved anywhere — research material only. Full overview: what is Survodutide? →
⚠ Trial titration climbs 0.6 → 1.2 → 2.4 → 3.6 → 4.8 → 6.0 mg weekly; the glucagon component makes nausea more likely if steps are rushed.
Calculate your exact dose
Typical range: 600 mcg–6 mg, 1x weekly, titrated up over ~20 weeks
Survodutide mixing chart — 10 mg vial
Units to draw for a 2.4 mg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 2.4 mg dose = | Per unit |
|---|---|---|---|
| 1 ml | 10.00 mg/ml | 24 units | 100.0 mcg |
| 2 ml ← typical | 5.00 mg/ml | 48 units | 50.0 mcg |
| 2.5 ml | 4.00 mg/ml | 60 units | 40.0 mcg |
| 3 ml | 3.33 mg/ml | 72 units | 33.3 mcg |
| 5 ml | 2.00 mg/ml | 120 units (>1 syringe) | 20.0 mcg |
Survodutide reconstitution by vial size — 5 mg / 10 mg
How much water for each vial size, and what a 2.4 mg dose becomes in syringe units. Bigger vials hold more doses; they do not change the dose.
| Vial | Water | Concentration | 2.4 mg dose = | Doses per vial |
|---|---|---|---|---|
| 5 mg | 1 ml | 5.00 mg/ml | 48 units | 2 |
| 5 mg | 2 ml | 2.50 mg/ml | 96 units | 2 |
| 5 mg | 3 ml | 1.67 mg/ml | 144 units (>1 syringe) | 2 |
| 10 mg | 1 ml | 10.00 mg/ml | 24 units | 4 |
| 10 mg | 2 ml | 5.00 mg/ml | 48 units | 4 |
| 10 mg | 3 ml | 3.33 mg/ml | 72 units | 4 |
Protocol reference
FAQ
How much bacteriostatic water do you add to Survodutide?+
Most protocols mix a 10 mg vial of Survodutide with 2 ml of bacteriostatic water. This gives 5.00 mg/ml, so a typical 2.4 mg dose is 48 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical Survodutide dose?+
Commonly reported Survodutide protocols use 600 mcg to 6 mg, 1x weekly, titrated up over ~20 weeks, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 10 mg vial of Survodutide?+
At 2.4 mg per dose, a 10 mg vial contains about 4 doses, regardless of how much water you add.
How should Survodutide be stored?+
Reconstituted: refrigerate; typically used within 4–8 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. Survodutide may not be approved for human use in your jurisdiction.