MOTS-c Reconstitution & Dosing
Quick answer: mix a 10 mg vial of MOTS-c with 2 ml of bacteriostatic water. That gives 5.00 mg/ml, so a typical 5 mg dose is 100 units on a U-100 insulin syringe — about 2 doses per vial. Reported protocols range 5 mg–10 mg, 1–3x weekly.
MOTS-c is a mitochondrial-derived peptide studied for exercise capacity, insulin sensitivity and metabolic regulation — often described as an 'exercise mimetic' in the research literature. Full overview: what is MOTS-c? →
Calculate your exact dose
Typical range: 5 mg–10 mg, 1–3x weekly
MOTS-c mixing chart — 10 mg vial
Units to draw for a 5 mg dose at different water amounts. More water never changes the dose — only the volume you measure.
| Water added | Concentration | 5 mg dose = | Per unit |
|---|---|---|---|
| 1 ml | 10.00 mg/ml | 50 units | 100.0 mcg |
| 2 ml ← typical | 5.00 mg/ml | 100 units | 50.0 mcg |
| 2.5 ml | 4.00 mg/ml | 125 units (>1 syringe) | 40.0 mcg |
| 3 ml | 3.33 mg/ml | 150 units (>1 syringe) | 33.3 mcg |
| 5 ml | 2.00 mg/ml | 250 units (>1 syringe) | 20.0 mcg |
Protocol reference
FAQ
How much bacteriostatic water do you add to MOTS-c?+
Most protocols mix a 10 mg vial of MOTS-c with 2 ml of bacteriostatic water. This gives 5.00 mg/ml, so a typical 5 mg dose is 100 units on a U-100 insulin syringe. More or less water is fine — it only changes the volume you draw, not the dose.
What is a typical MOTS-c dose?+
Commonly reported MOTS-c protocols use 5 mg to 10 mg, 1–3x weekly, administered via subcutaneous injection. These are reference figures from published protocols, not medical advice — individual use should be guided by a healthcare provider.
How many doses are in a 10 mg vial of MOTS-c?+
At 5 mg per dose, a 10 mg vial contains about 2 doses, regardless of how much water you add.
How should MOTS-c be stored?+
Reconstituted: refrigerate, typically used within 4 weeks.
Related peptides
Educational reference only. Values reflect commonly published research protocols and are not medical advice or a recommendation to use any compound. MOTS-c may not be approved for human use in your jurisdiction.